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Conception
After the follicle puncture, we can see in the lab how many of the ova have been fertilised. With mature ova a conception rate of about 80% is normal (also for the ICSI-method).
In the microscope the fertilised ovum has a nucleus with the motherly and fatherly genotype. These cell-nucleuses melt in the course of the day to one single cell-nucleus: that of the embryo.
Sometimes it happens that in the fertilised ovum three cell-nucleuses are seen. The ovum is then called triploid. In isolated cases the reasons for that cannot be said. It is possible that (with conventional IVF) 2 sperms have penetrated into the ovum. However: Ovum or sperm already had two instead of only one cell-nucleus. From triploided ova no surviving embryo can originate, these ova have to be rejected. |
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normal fertilised ovum |
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triploid ovum |
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By all normal fertilised ova we do the so-called PN score. Hereby, with small microscopic structures in the cell-nucleuses it is possible to observe the quality of the ovum. Ovum with a very favourable developing prediction are selected and further cultivated to embryos. Others can be cryo-preserved or also rejected. All this is always done in according with the patients.
Further to
Embryos
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